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Can Cats Develop Immunity to FIP After Treatment?

Updated: Feb 10

Feline infectious peritonitis (FIP) is a devastating disease, but with recent treatment breakthroughs, cats have a renewed fighting chance. Emerging research offers a glimmer of hope: cats who successfully complete FIP treatment may develop some level of immunity to future FIP infections.


Promising Studies on FIP Immunity

Recent studies are exploring whether successful FIP treatment provides lasting protection. Key takeaways include:


  • 2021 Study: In a study published in Viruses, cats who recovered from FIP after treatment with GS-441524 showed signs of resistance for over 18 months afterward.

  • 2022 Study: Research in Clinical Microbiology and Infection demonstrated similar post-recovery resilience in cats treated with EIDD-2801.


While these results are promising, experts emphasize that continued research is crucial.  Feline immunity is complex, and more data is needed to fully understand cats' long-term protection against FIP.


Important Note: Cats treated for FIP serotype 1 are unlikely to develop resistance or immunity to FIP serotype 2.


Post-FIP Care: Vigilance is Key

Even with encouraging signs of immunity, it's essential to exercise caution after your cat's FIP treatment. Here's how to support their ongoing health:

  • Monitoring: Be alert for any health changes in your cat and contact your veterinarian if you see any signs of potential relapse.

  • Veterinary Care: Schedule regular checkups and follow your veterinarian's recommendations.

  • Prevention: Ensure your cat receives all necessary vaccinations and take measures to minimize their exposure to feline coronavirus.


Stay Informed

Keep up with the latest FIP research advancements by exploring these key studies:

  • Feline Infectious Peritonitis Treatment with GS-441524 Leads to Long-Term Survival and Resistance to Re-Infection: https://www.mdpi.com/1999-4915/13/7/1326 by Stephanie Brown et al., Viruses, 2021.

  • Long-Term Survival and Resistance to Re-Infection of Cats with Feline Infectious Peritonitis Treated with EIDD-2801: <invalid URL removed> by Stephanie Brown et al., Clinical Microbiology and Infection, 2022.

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